Mood and Cognitive Changes: B12 is linked to mental health, and deficiency can cause mood swings, memory problems, and even depression
Cyanocobalamin is indicated for Vitamin B12 deficiencies due to malabsorption which may be associated with the following conditions: Addisonian (pernicious) anemia Gastrointestinal pathology, dysfunction, or surgery, including gluten enteropathy or sprue, small bowel bacterial overgrowth, total or partial gastrectomy Fish tapeworm infestation Malignancy of pancreas or bowel Folic acid deficiency It may be possible to treat the underlying disease by surgical correction of anatomic lesions leading to small bowel bacterial overgrowth, expulsion of fish tapeworm, discontinuation of drugs leading to vitamin malabsorption (see Drug/Laboratory Test Interactions), use of a gluten-free diet in nontropical sprue, or administration of antibiotics in tropical sprue
Do not use folic acid instead of vitamin B12
Non response to B12 injections should therefore necessitate re-evaluation and consideration of other diagnoses
Chan CW, Liu SY, Kho CS, Lau KH, Liang YS, Chu WR, Ma SK
